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Description |
Unit |
Price
(VAT별도) |
납기 |
재고 |
DataSheet |
주문/견적 |
| LCA-23-351439 |
NBP1-03210 |
ADAM1 Antibody//Human, Mouse,/Rabbit |
1/EA |
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문의 |
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Subject
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ADAM1 Antibody |
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Description
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/ Human, Mouse,/Rabbit |
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Clonality
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Poly |
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Company
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Novus biologicals |
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Application
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IHC-P, Western Blot |
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Conjugation
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Immunogen
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Contents
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Description:Summary: | Species: | Rt, Mu, Hu | | Applications: | IHC-P, WB | | Clonality: | Polyclonal | | | Gene: | ADAM17 | | Purity: | Affinity purified | | Host: | Rabbit | | | Specificity: | Amino acids 807 to 823 of human TACE | Details: | Immunogen: | Synthetic peptide corresponding to Amino acids 807 to 823 of human TACE | Gene Symbol: ADAM17 | Entrez: | 6868 (Human) | | | 11491 (Mouse) | | | 57027 (Rat) | | Swiss Prot: | P78536 (Human) | | Related Genes: | TNF, FAM126A, EGFR, ADAM10, AFP, BACE1, EGF, TRIM26, MMP9, VEGFA, ADAM9, MAPK1, TNFRSF1A, AREG, MAPK3, MMP3, AKT1, IL6, HBEGF, TIMP3, APP, ALB, TIMP-1, TIMP1, GHR, TGFA, PKC, MMP13, MMP-2, PRNP, TNFRSF1B, TNFRSF11A, MMP2, CASP3, MMP-13, TNFSF11, NGFR, ADAM19, FURIN, PIK3CG | Background: Tumor-necrosis factor-a is a proinflammatory cytokine and contributes to a variety of inflammatory disease responses and programmed cell death. TNF-a is synthesized as a 26K type II membrane-bound precursor that is cleaved by a convertase to generate secreted 17K mature TNF-a. TNF-a converting enzyme (TACE) protein was recently purified and the human and mouse TACE cDNAs were cloned by several groups separately. TACE is a membrane-bound metalloprotease-disintegrin in the family of mammalian ADAM (for a disintegrin and metalloprotease). TACE also processes other cell surface proteins, including TNF receptor, TGFa, the L-selectin adhesion molecule, and alpha-cleavage of amyloid protein precursor (APP). TACE mRNA is expressed in a variety of human and murine tissues. TACE was selected as one of the few targets in cytokine activation by the Eighth International Conference of the Inflammation Research Association. ADAM17 is a Metallopeptidase M12B type protease. Species: | Reactivity: | This antibody is reactive to Human, Mouse, Rat. | Applications: | Uses: | This antibody is useful for the following applications and at the following dilutions: Western Blot, Immunohistochemistry-Paraffin 20 ug/ml | | Dilutions: | Western Blot,Immunohistochemistry-Paraffin 20 ug/ml, | | Concentrations: | 0.5 mg/ml | Packaging: | Buffer: | PBS | | Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. | | Preservative: | 0.02% Sodium Azide | | Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. | |
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