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Description |
Unit |
Price
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납기 |
재고 |
DataSheet |
주문/견적 |
| LCA-23-350974 |
NBP1-20872 |
ABCD4 Antibody//Canine, Human/Goat |
1/EA |
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문의 |
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Subject
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ABCD4 Antibody |
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Description
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/ Canine, Human/Goat |
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Clonality
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Poly |
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Company
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Novus biologicals |
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Application
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PEP-ELISA, Western Blot |
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Conjugation
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Immunogen
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Contents
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Description:Summary: | Species: | Ca, Rt, Mu, Hu | | Applications: | WB, PEP-ELISA | | Clonality: | Polyclonal | | | Gene: | ABCD4 | | Purity: | Immunogen affinity purified | | Host: | Goat | | | Specificity: | ABCD4 | | Publications: | Antibody has not yet been mentioned in a publication. | Details: | Isotype: | IgG | | Immunogen: | Synthetic peptide, C-RDDIDNPDQRISQD, representing the C terminusof the sequence according to NP_005041.1 | | Epitope: | C terminus | Gene Symbol: ABCD4 | Entrez: | 5826 (Human) | | | 299196 (Rat) | | Swiss Prot: | NP_005041.1 (Human) | | Related Genes: | ABCD1, ABCD3, ABCD2, ABCA4, PYCARD, ABCE1, ABCB1, ABCF1, ABCC1, PNPLA6, TOP1, EXOSC10, TYMS, ABCB6, ABCF2, ABCA7, ABCC4, SLC27A2, DCK, EDNRB, FJX1, ABCB4, ABCA3, TRIM44, ABCB5, SLC10A3, CHEK1, BCL2L10, ABCF3, MYO6, ATP5G3, RLN1, FADD, PPARA, SLC10A6, GSTP1, KHSRP, ACOX1, SPO11, LTBP3 | Background: The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. The function of this peroxisomal membrane protein is unknown. However, it is speculated that it may function as a heterodimer for another peroxisomal ABC transporter and, therefore, may modify the adrenoleukodystrophy phenotype. It may also play a role in the process of peroxisome biogenesis. Alternative splicing results in at least two different transcript variants, one which is protein-coding and one which is probably not protein-coding. Species: | Reactivity: | Human, Mouse, Rat, Dog | Applications: | Uses: | Peptide ELISA: antibody detection limit dilution 1:8,000. Western Blot: Approx 70kDa band observed in lysates of cell lines Jurkat and MOLT4 (calculated MW of 68.6kDa according to NP_005041.1). Recommended concentration: 0.3-1ug/ml. | | Dilutions: | Peptide ELISA 1:8000, Western Blot 0.3-1ug/ml | | Concentrations: | 0.5 mg/ml | Packaging: | Buffer: | Tris-saline [pH7.3] with 0.5% BSA | | Storage: | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. | | Preservative: | 0.02% Sodium Azide | | Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. | |
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