| Synonyms | Multidrug resistance-associated protein 4, MOAT-B |
| Swiss Prot Num | O15439 |
| Immunogen | This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human ABCC4. |
| Product Type | Antibodies |
| Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
| References | 1. Lee K., Belinsky M.G., Bell D.W.Cancer Res. 58:2741-2747(1998) 2. Adachi M., Sampath J., Lan L.B.J. Biol. Chem. 277:38998-39004(2002) 3. Kool M., de Haas M., Scheffer G.L.Cancer Res. 57:3537-3547(1997) 4. Janke D., Mehralivand S., Strand D.Hum. Mutat. 29:659-669(2008) |
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| Format | State: Liquid purified Ig |
| ? | Purification: Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS |
| ? | Buffer System: PBS with 0.09% (W/V) sodium azide |
|
| Specificity | This antibody reacts to ABCC4. |
| Application | ELISA: 1/1,000. Western blotting: 1/50 - 1/100. |
| Background | ABCC4 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC proteins are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. The specific function of this protein has not yet been determined; however, this protein may play a role in cellular detoxification as a pump for its substrate, organic anions. |
| Caution | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Concentration | 0.25 mg/ml |
