| Catalog Number | GTX108035 |
| Product Name | actin-like 6B antibody |
| Full Name | actin-like 6B |
| Product Description | Rabbit polyclonal antibody to actin-like 6B (actin-like 6B) |
| Synonyms | ACTL6 | BAF53B |
| Background | The protein encoded by this gene is a member of a family of actin-related proteins (ARPs) which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene encodes a subunit of the BAF (BRG1/brm-associated factor) complex in mammals, which is functionally related to SWI/SNF complex in S. cerevisiae and Drosophila; the latter is thought to facilitate transcriptional activation of specific genes by antagonizing chromatin-mediated transcriptional repression. This subunit may be involved in the regulation of genes by structural modulation of their chromatin, specifically in the brain. [provided by RefSeq] |
| Clonality | Polyclonal |
| Host | Rabbit |
| Immunogen | Synthetic peptide contain a sequence corresponding to a region within amino acids 363 and 426 of Human actin-like 6B |
| Antigen Species | Human |
| Tested Applications | Dot Blot |
| Application Note | Further validation in progress. |
| Specificity | This antibody is specific to the peptide antigen from actin-like 6B. |
| Species Cross Reactivity | Human - Not yet tested in other species |
| Positive Controls | Synthetic peptide: 1:8,000 |
| Target | actin-like 6B |
| Predicted Target Size(KDa) | 46.88 |
| Cellular Localization | Nucleus |
| Form Supplied | Liquid |
| Concentration | 0.43 mg/ml |
| Purification | Purified by antigen-affinity chromatography. |
| Storage Buffer | 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
| Storage Instruction | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Notes | For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption. |
