| Catalog Number | GTX101647 |
| Product Name | ACE2 antibody |
| Full Name | angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 |
| Product Description | Rabbit polyclonal antibody to ACE2 (angiotensin I converting enzyme (peptidyl-dipeptidase A) 2) |
| Synonyms | ACEH | DKFZP434A014 |
| Background | The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. The organ- and cell-specific expression of this gene suggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility. In addition, the encoded protein is a functional receptor for the spike glycoprotein of the human coronaviruses SARS and HCoV-NL63. [provided by RefSeq] |
| Clonality | Polyclonal |
| Host | Rabbit |
| Immunogen | Recombinant protein fragment contain a sequence corresponding to a region within amino acids 258 and 506 of ACE2 |
| Antigen Species | Human |
| Tested Applications | Dot blot |
| Application Note | Further validation in progress. |
| Specificity | This antibody is specific to the Protein antigen from ACE2. |
| Species Cross Reactivity | Human - Not yet tested in other species |
| Positive Controls | Target recombinant protein |
| Target | ACE2 |
| Predicted Target Size(KDa) | 92.48 |
| Cellular Localization | Processed angiotensin-converting enzyme 2: Secreted | Cell membrane |
| Form Supplied | Liquid |
| Concentration | 0.62 mg/ml |
| Purification | Purified by antigen-affinity chromatography. |
| Storage Buffer | 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
| Storage Instruction | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Notes | For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption. |
