| Catalog Number | GTX103281 |
| Product Name | ABCE1 antibody |
| Full Name | ATP-binding cassette, sub-family E (OABP), member 1 |
| Product Description | Rabbit polyclonal antibody to ABCE1 (ATP-binding cassette, sub-family E (OABP), member 1) |
| Synonyms | ABC38 | OABP | RLI | RNASEL1 | RNASELI | RNS4I |
| Background | The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the OABP subfamily. Alternatively referred to as the RNase L inhibitor, this protein functions to block the activity of ribonuclease L. Activation of ribonuclease L leads to inhibition of protein synthesis in the 2-5A/RNase L system, the central pathway for viral interferon action. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq] |
| Clonality | Polyclonal |
| Host | Rabbit |
| Immunogen | Recombinant protein fragment contain a sequence corresponding to a region within amino acids 230 and 471 of Human ABCE1 |
| Antigen Species | Human |
| Tested Applications | Dot Blot |
| Application Note | Further validation in progress. |
| Specificity | This antibody is specific to the Protein antigen from ABCE1. |
| Species Cross Reactivity | Human - Not yet tested in other species |
| Positive Controls | Target recombinant protein |
| Target | ABCE1 |
| Predicted Target Size(KDa) | 67.32 |
| Cellular Localization | Cytoplasm | Mitochondrion |
| Form Supplied | Liquid |
| Concentration | 0.15 mg/ml |
| Purification | Purified by antigen-affinity chromatography. |
| Storage Buffer | 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
| Storage Instruction | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Notes | For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption. |
