| Catalog Number | GTX11020 |
| Product Name | ACTH antibody |
| Product Description | Rabbit polyclonal to ACTH |
| Synonyms | 5443 | POMC | 176830 | P01189 | ACTH | CLIP | LPH | MSH | NPP | POC | |
| Background | Human adrenocorticotrophin (ACTH) is a 39 amino acid cleavage product from pro-opiomelanocortin (POMC) which elicits a classic glucocorticoid response from the adrenal glands in situations of stress. ACTH is produced in the pituitary, and also by lymphocytes and macrophages. |
| Clonality | Polyclonal |
| Host | Rabbit |
| Isotype | IgG |
| Immunogen | Synthetic peptide (Human ACTH). |
| Antigen Species | Human |
| Tested Applications | IHC (Frozen sections), IHC (Formalin-fixed paraffin-embedded sections). The usefulness of this product in other applications has not been determined. |
| Application Note | IHC-P: Use at a dilution of 1/10 - 1/40. IHC-Fr: Use at a dilution of 1/10 - 1/40. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user. |
| Specificity | In immunohistology this antibody stains corticotroph cells of the pituitary gland and benign and malignant tumours arising from these cells. |
| Species Cross Reactivity | Human - Not yet tested in other species |
| Positive Controls | Pituitary Gland |
| Target | ACTH |
| Cellular Localization | Secreted |
| Form Supplied | Liquid |
| Purification | Whole antiserum |
| Storage Buffer | Preservative: 0.09% Sodium Azide; Constituents: 1% BSA, Phosphate, PBS |
| Storage Instruction | Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles. |
| Notes | This product should be stored undiluted.Should this product contain a precipitate we recommend microcentrifugation before use. |
