| Catalog Number | GTX22092 |
| Product Name | ACE [M4110421] antibody |
| Product Description | Mouse monoclonal [M4110421] to Angiotensin Converting Enzyme |
| Background | Angiotensin Converting enzyme is involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. |
| Clonality | Monoclonal |
| Clone No | M4110421 |
| Host | Mouse |
| Isotype | IgM |
| Immunogen | Human Angiotensin Converting Enzyme |
| Antigen Species | Human |
| Tested Applications | ELISA, Flow cytometry/FACS, IHC (Frozen sections), IHC (Formalin-fixed paraffin-embedded sections). The usefulness of this product in other applications has not been determined. |
| Application Note | ELISA: Use at an assay dependent dilution. FACS: Use at an assay dependent dilution. IHC-P: Use at an assay dependent dilution. IHC-Fr: Use at an assay dependent dilution. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user. |
| Specificity | Shown to crossreact with human, bovine and mouse Angiotensin Converting Enzyme and Endothelial cells. |
| Species Cross Reactivity | Cross-reacts with Human, Mouse and Cow. Not yet tested in other species. |
| Target | ACE |
| Cellular Localization | Type I membrane protein |
| Form Supplied | Liquid |
| Purification Note | Purified by PEG precipitation. |
| Storage Buffer | Preservative: NoneConstituents: PBS. pH 7.4 |
| Storage Instruction | Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles. |
