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Description |
Unit |
Price
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납기 |
재고 |
DataSheet |
주문/견적 |
| LCA-24-368576 |
AP01190PU-N |
Adenosine receptor A3//Human/Rabbit |
1/EA |
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문의 |
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Subject
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Adenosine receptor A3 |
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Description
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/ Human/Rabbit |
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Clonality
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Mono |
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Company
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Acris Antibodies GmbH |
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Application
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Immunofluorescence, Paraffin Sections, Western blot / Immunoblot |
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Conjugation
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Immunogen
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Contents
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Description: | Manufacturer | Acris Antibodies GmbH | | Quantity | 100 ug | | Reactivity | Human | | Presentation | Aff - Purified | | Applications | Immunofluorescence, Paraffin Sections, Western blot / Immunoblot | | Host | Rabbit | | PDF datasheet | view | | Shipping to | Worldwide | | Synonyms | ADORA3, Adenosine A3 receptor, FocusOn065 | | Swiss Prot Num | P33765 | | Product Type | Antibodies | | Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: One year from despatch. | |
| Format | State: Liquid purified Ig fraction | | ? | Purification: Affinity chromatography using epitope-specific immunogen. The purity is > 95% (by SDS-PAGE). | | ? | Buffer System: Phosphate buffered saline (PBS), pH~7.2 containing 15 mM Sodium Azide as preservative | |
| Specificity | This antibody detects endogenous levels of Adenosine A3-R protein. | | Application | ELISA: 1/10000-1/20000. Western Blot: 1/500-1/1000. Immunohistochemistry: 1/50 - 1/200. Immunofluorescence: 1/50 - 1/200. | | Background | Adenosine is involved in a variety of processes, including the synthesis of urea, the anti-inflammatory response and the inhibition of protein synthesis The adenosine receptors, including adenosine A1-R, adenosine A2A-R, adenosine A2B-R and adenosine A3-R, are integral membrane proteins that are members of the G protein-coupled receptor family. The A1-R protein mediates ureagenesis in a partially calcium-dependent manner. Adenosine is known to mediate coronary vasodilation via the A2A-R receptor. Collagen synthesis and total protein synthesis are inhibited in certain cells by adenosine, acting via the A2B receptors. Activation of the A3-R receptor inhibits the induction of the cytokine TNFalpha and blocks the endotoxin CD14 receptor signal transduction pathway. | | Concentration | 1.0 mg/ml | | Focuson | 065 Antibodies to Adenosine Receptors | |
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