| Synonyms | DSRAD, G1P1, IFI4, P136, K88DSRBP |
| Swiss Prot Num | P55265 |
| Immunogen | This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human ADAR. |
| Product Type | Antibodies |
| Storage | Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
| References | 1. Lykke-Andersen,S., RNA 13 (10), 1732-1744 (2007). 2. Li,M., Arch. Dermatol. Res. 299 (5-6), 273-275 (2007). |
|
| Format | State: Liquid Ig fraction |
| ? | Purification: Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. Then the antibody is purified by peptide affinity purification. |
| ? | Buffer System: PBS with 0.09% (W/V) sodium azide |
|
| Specificity | This antibody detects Adenosine Deaminase (ADAR) at N-term. |
| Add. information | Molecular weight: 135995 Da |
| Application | ELISA 1:1,000. Western blot 1:50 - 1:100. |
| Background | ADAR is the enzyme responsible for RNA editing by site-specific deamination of adenosines. This enzyme destabilizes double stranded RNA through conversion of adenosine to inosine. Mutations have been associated with dyschromatosis symmetrica hereditaria. |
| Concentration | 0.25 mg/ml |
