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| Cat. No |
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Description |
Unit |
Price
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납기 |
재고 |
DataSheet |
주문/견적 |
| LCA-24-368478 |
AP15256PU-N |
ACP1 / LMW-PTPase//Human/Rabbit |
1/EA |
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Subject
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ACP1 / LMW-PTPase |
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Description
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/ Human/Rabbit |
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Clonality
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Mono |
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Company
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Acris Antibodies GmbH |
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Application
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Enzyme Immunoassay, Paraffin Sections, Western blot / Immunoblot |
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Conjugation
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Immunogen
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Contents
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Description: | Manufacturer | Acris Antibodies GmbH | | Quantity | 0.1 mg | | Reactivity | Human | | Presentation | Purified | | Applications | Enzyme Immunoassay, Paraffin Sections, Western blot / Immunoblot | | Isotype | Ig | | Host | Rabbit | | PDF datasheet | view | | Shipping to | Worldwide | | Synonyms | Adipocyte acid phosphatase, Red cell acid phosphatase 1, HAAP | | Swiss Prot Num | P24666 | | Immunogen | This antibody is generated from rabbits immunized with a recombinant protein encoding full length of human LMW-PTP. | | Product Type | Antibodies | | Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. | | References | 1. Ramponi, G. Adv. Protein Phosphatases 8, 1-25, (1994). 2. Zhang, M., et al. Adv. Protein Phosphatases 9, 1-23, (1995). 3. Cirri, P., et al. Eur. J. Biochem. 214, 647-657, (1993). 4. Su, X.-D., et al. Nature 370, 575-578, (1994). 5. Ramponi, G., et al. Int. J. Cancer 51, 652-656, (1992). 6. Tailor,P., et al. Eur. J. Biochem. 262 (2), 277-282 (1999) 7. Zhang,M., et al. J. Biol. Chem. 273 (34), 21714-21720 (1998) | |
| Format | State: Liquid purified Ig | | ? | Purification: Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS | | ? | Buffer System: PBS with 0.09% (W/V) sodium azide | |
| Specificity | This antibody reacts to LMW-PTP. | | Application | ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/10 - 1/50. | | Background | The low molecular weight PTPases LMPTP-A and LMPTP-B is a class of PTPases with low homology to other PTPases. LMPTPs are highly specific for PTyr and their catalytic mechanism involves a cysteine residue. The physiological functions of LMPTP are unknown. Overexpression of LMPTP in cells transformed by PTK oncogenes leads to decreased proliferation that suggests a potential physiological function of the LMPTPs in control of normal cell growth by interacting directly or indirectly with the PTK signaling network. LMPTP is regulated during T cell activation that is associated with phosphorylation of Tyr-131/132 presumably by Lck or Fyn. | | Caution | This product is for research use only. Not for use in diagnostic or therapeutic procedures. | | Concentration | 0.25 mg/ml | |
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