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| Cat. No |
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Description |
Unit |
Price
(VAT별도) |
납기 |
재고 |
DataSheet |
주문/견적 |
| LCA-25-387465 |
GTX14015 |
E Cadherin antibody//Human,Mouse,rat/Chicken |
1/EA |
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문의 |
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Subject
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E Cadherin antibody |
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Description
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/ Human,Mouse,rat/Chicken |
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Clonality
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Poly |
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Company
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GeneTex |
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Application
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Western Blot |
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Conjugation
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Immunogen
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Contents
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| Catalog Number | GTX14015 | | Product Name | E Cadherin antibody | | Product Description | Chicken polyclonal to E Cadherin | | Synonyms | 999 | CDH1 | 137215 | P12830 | Arc-1 | CDHE | ECAD | LCAM | UVO | | | Background | One of the epithelial cell adhesion molecules, E Cadherin, plays an important role in the formation of cell-cell contacts in epithelia irrespective their origin form ecto-, meso- or endodermal tissue. This early adhesion event between epithelial cells is a prerequisite for the assembly of all elements of the junctional complex. Furthermore, E Cadherin plays a crucial role in the maintenance of the epithelial junctional complex and is as such an important molecule in maintaining epithelial integrity. Over 90% of the malignant tumors are carcimomas. One of the prerequisites for the release of carcinoma cells from the primary site might be a defect in intercellular adhesion mediated by the absence of E Cadherin expression. Therefore, the expression of E Cadherin might be an important parameter for the determination of the invasive potential of epithelial neoplasms, and for the transition of a benign to a malignant neoplasm. | | Clonality | Polyclonal | | Host | Chicken | | Isotype | IgY | | Immunogen | Recombinant fragment, corresponding to amino acids 196-278 of Human E Cadherin. | | Antigen Species | Human | | Tested Applications | Western blot. The usefulness of this product in other applications has not been determined. | | Application Note | For WB: Use at an assay dependent dilution. Predicted molecular weight: 97 kDa. Not tested in other applications. Optimal dilutions/concentrations should be determined by the researcher. | | Species Cross Reactivity | Human, mouse and rat - Not tested in other species | | Target | E Cadherin | | Form Supplied | Liquid | | Purification | Affinity purified with antigen | | Storage Buffer | PBS, no preservatives added | | Storage Instruction | Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles. | Image:img24522.jpgE coli-derived fusion protein as test antigen. GTX14015 dilution: 1:2,000, Goat anti-IgY-HRP dilution: 1:1,000. Colorimetric method for signal development. Print:Print |
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