|
| |
| Cat. No |
Model |
Description |
Unit |
Price
(VAT별도) |
납기 |
재고 |
DataSheet |
주문/견적 |
| LCA-23-312812 |
NB100-1012 |
ADAM1 Antibody//Human/Goat |
1/EA |
|
|
|
|
문의 |
|
|
|
|
|
|
|
Subject
|
ADAM1 Antibody |
|
Description
|
/ Human/Goat |
|
Clonality
|
Poly |
|
Company
|
Novus biologicals |
|
Application
|
PEP-ELISA, Western Blot |
|
Conjugation
|
|
|
Immunogen
|
|
|
Contents
|
Description:Summary: | Species: | Hu | | Applications: | WB, PEP-ELISA | | Clonality: | Polyclonal | | | Gene: | ADAM17 | | Purity: | Immunogen affinity purified | | Host: | Goat | | | Specificity: | This is expected to recognise isoform 1 (represented by NP_003174) and not isoform 2 (represented by NP_068604). | | Publications: | Antibody has not yet been mentioned in a publication. | Details: | Isotype: | IgG | | Immunogen: | Synthetic peptide: LQRQNRVDSKETEC representing the C-terminus of the human protein (residues 811-824), according to NP_003174.3. | | Localization: | Type I membrane protein. | Gene Symbol: ADAM17 | Entrez: | 6868 (Human) | | Swiss Prot: | NP_003174.3. (Human) | | Related Genes: | TNF, FAM126A, EGFR, ADAM10, AFP, BACE1, EGF, TRIM26, MMP9, VEGFA, ADAM9, MAPK1, TNFRSF1A, AREG, MAPK3, MMP3, AKT1, IL6, HBEGF, TIMP3, APP, ALB, TIMP-1, TIMP1, GHR, TGFA, PKC, MMP13, MMP-2, PRNP, TNFRSF1B, TNFRSF11A, MMP2, CASP3, MMP-13, TNFSF11, NGFR, ADAM19, FURIN, PIK3CG | Background: This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biologic processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene functions as a tumor necrosis factor-alpha converting enzyme; binds mitotic arrest deficient 2 protein; and also plays a prominent role in the activation of the Notch signaling pathway. Species: | Reactivity: | Human, mouse, rat, chinese and hamster. | Applications: | Uses: | This antibody is useful for Western Blot and Peptide ELISA. Approx 100kDa band observed in human testis lysates (calculated MW of 93.0kDa according to NP_003174.3). | | Dilutions: | Peptide ELISA 1:128000, Western Blot 0.1-0.3?g/ml | | Concentrations: | 0.5 mg/ml | | Positive Controls: | 1 positive controls | Packaging: | Buffer: | Tris saline containing [pH7.3] with 0.5% BSA | | Storage: | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. | | Preservative: | 0.02% Sodium Azide | | Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. | |
|
|
|
|
