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| Cat. No |
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Description |
Unit |
Price
(VAT별도) |
납기 |
재고 |
DataSheet |
주문/견적 |
| LCA-23-312167 |
NB100-1867 |
Active Caspase 2 Antibody//Human/Rabbit |
1/EA |
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문의 |
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Subject
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Active Caspase 2 Antibody |
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Description
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/ Human/Rabbit |
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Clonality
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Poly |
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Company
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Novus biologicals |
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Application
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ICC, IHC-P, Western Blot |
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Conjugation
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Immunogen
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Contents
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Description:Summary: | Species: | Hu | | Applications: | WB, IHC, ICC | | Clonality: | Polyclonal | | | Gene: | CASP2 | | Purity: | Whole antisera | | Host: | Rabbit | | | Specificity: | Reacts with caspase-2 from cell extracts. This will recognize the uncleaved form of Caspase 2. | Details: | Isotype: | IgG | | Immunogen: | Synthetic C-terminal peptide (Human). | Gene Symbol: CASP2 | Entrez: | 835 (Human) | | Related Genes: | CASP3, CASP9, CASP8, CASP1, CYCS, BCL2L1, BCL2, CASP7, BAX, PARP1, BID, CASP6, CRADD, FAS, TP53, ICH-1, LRDD, COL11A2, APAF1, FASLG, DIABLO, BAK1, FADD, TNFSF10, AIFM1, MAPK8, TNF, CDKN1A, CUX1, CASP10, MCL1, CRTAP, CYTIP, NFKB1, GZMB, RIPK1, AKT1, XIAP, JUN, HTT | Background: Caspase 2 has a positive and a negative role in the regulation of the apoptotic process. Overexpression of the full length Caspase 2 (Nedd2/Ich1 ) mRNA in some cell types results in apoptosis, whereas overexpression of an alternative Caspase 2 splice variant suppresses apoptosis induced by serum withdrawal. Caspase 2 may be activated in vitro by Caspase 1, Caspase 3 and the neutral serine protease granzyme B which is stored in the specialized lytic granules of cytotoxic lymphocytes. Species: | Reactivity: | Cross-reacts with Human. Not yet tested in other species. | Applications: | Uses: | This antibody can be used in Western Blot, Immunocytochemistry, and Immunohistochemistry. In Western Blot a 37 kDa band is seen. Recommended Starting Dilutions*: IHC: 1/100-1/500 Western Blot: 1/500-1/5000 *Optimal dilutions should be determined by the end user. | | Dilutions: | Immunocytochemistry, immunohistochemistry, Western Blot, | Notes: Reconstitute in 200 ul of distilled water. Packaging: | Buffer: | Lyophilized purified antisera. | | Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. | | Preservative: | No Preservative | | Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. | |
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